发明公开
- 专利标题： REOVIRUSES HAVING MODIFIED SEQUENCES
- 专利标题（中）： 呼肠孤病毒与修饰序列
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申请号： EP08733587申请日： 2008-03-11
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公开(公告)号： EP2132315A4公开(公告)日： 2011-10-05
- 发明人: COFFEY MATTHEW C
- 申请人： ONCOLYTICS BIOTECH INC
- 专利权人： ONCOLYTICS BIOTECH INC
- 当前专利权人： ONCOLYTICS BIOTECH INC
- 优先权： US89442507 2007-03-12; US98956807 2007-11-21
- 主分类号： C12N15/46
- IPC分类号： C12N15/46 ; A61K35/76 ; A61P35/00 ; C07K14/14 ; C12N7/01 ; C12N15/86
摘要：
The invention provides for modified reovirus nucleic acid sequences and modified reovirus polypeptide sequences as well as reoviruses containing such modified nucleic acid or polypeptide sequences. The invention also provides for pharmaceutical compositions that include reoviruses having a modified sequence as well as methods of making and using such reoviruses.
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