发明公开
- 专利标题： INHIBITORS OF THE HEDGEHOG PATHWAY
- 专利标题（中）： 缝边的刺猬SIGNALWEGES
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申请号： EP08732145.1申请日： 2008-03-13
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公开(公告)号： EP2134695A1公开(公告)日： 2009-12-23
- 发明人: BAHCECI, Suleyman , BAJJALIEH, William , CHEN, Jeff , EPSHTEYN, Sergey , FORSYTH, Timothy Patrick , HUYNH, Tai Phat , KIM, Byung Gyu , LEAHY, James W. , LEE, Matthew Sangyup , LEWIS, Gary L. , MAC, Morrison B. , MANN, Grace , MARLOWE, Charles K. , RIDGWAY, Brian Hugh , SANGALANG, Joan C. , SHI, Xian , TAKEUCHI, Craig Stacy , WANG, Yong , TESFAI, Zerom
- 申请人： Exelixis, Inc.
- 申请人地址： 210 East Grand Avenue P.O. Box 511 South San Francisco, CA 94083-0511 US
- 专利权人： Exelixis, Inc.
- 当前专利权人： Exelixis, Inc.
- 当前专利权人地址： 210 East Grand Avenue P.O. Box 511 South San Francisco, CA 94083-0511 US
- 代理机构： Campbell, Patrick John Henry
- 优先权： US918160P 20070314; US962617P 20070730
- 国际公布： WO2008112913 20080918
- 主分类号： C07D239/42
- IPC分类号： C07D239/42 ; C07D401/04 ; C07D403/12
摘要：
The present invention is directed to a compound of Formula (I) or a single isomer thereof; where the compound is optionally as a pharmaceutically acceptable salt, hydrate, solvate or combination thereof, in addition to methods of preparing a Compound of Formula I, and methods of using a Compound of Formula (I) to treat cancer.
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