发明公开
EP2136811A1 GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF
审中-公开
糖皮质激素类似物，其制造，药物组合物及其使用方法
- 专利标题： GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF
- 专利标题（中）： 糖皮质激素类似物，其制造，药物组合物及其使用方法
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申请号： EP08745327.0申请日： 2008-04-09
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公开(公告)号： EP2136811A1公开(公告)日： 2009-12-30
- 发明人: KUZMICH, Daniel , DISALVO, Darren , REGAN, John Robinson
- 申请人： Boehringer Ingelheim International GmbH , Boehringer Ingelheim Pharma GmbH & Co. KG
- 申请人地址： Binger Straße 173 55216 Ingelheim am Rhein DE
- 专利权人： Boehringer Ingelheim International GmbH,Boehringer Ingelheim Pharma GmbH & Co. KG
- 当前专利权人： Boehringer Ingelheim International GmbH,Boehringer Ingelheim Pharma GmbH & Co. KG
- 当前专利权人地址： Binger Straße 173 55216 Ingelheim am Rhein DE
- 代理机构： Hammann, Heinz
- 优先权： US922746P 20070410
- 国际公布： WO2008124745 20081016
- 主分类号： A61K31/535
- IPC分类号： A61K31/535
摘要：
Compounds of Formula (I) wherein R1, R2, R3, R4, R5, R6, X, R7, and R8 are as defined herein, or a tautomer, prodrug, solvate, or salt thereof; pharmaceutical compositions containing such compounds, and methods of modulating the glucocorticoid receptor function and methods of treating disease-states or conditions mediated by the glucocorticoid receptor function or characterized by inflammatory, allergic, or proliferative processes in a patient using these compounds.
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