发明公开
EP2148875A1 COMPOUNDS AND COMPOSITIONS AS C-KIT AND PDGFR KINASE INHIBITORS
审中-公开
化合物和组合物c-kit和PDGFR激酶抑制剂
- 专利标题： COMPOUNDS AND COMPOSITIONS AS C-KIT AND PDGFR KINASE INHIBITORS
- 专利标题（中）： 化合物和组合物c-kit和PDGFR激酶抑制剂
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申请号： EP08747578.6申请日： 2008-05-02
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公开(公告)号： EP2148875A1公开(公告)日： 2010-02-03
- 发明人: LI, Xiaolin , LIU, Xiaodong , MOLTENI, Valentina
- 申请人： IRM LLC
- 申请人地址： 131 Front Street P.O. Box HM 2899 Hamilton HM LX BM
- 专利权人： IRM LLC
- 当前专利权人： IRM LLC
- 当前专利权人地址： 131 Front Street P.O. Box HM 2899 Hamilton HM LX BM
- 代理机构： Kiddle, Simon John
- 优先权： US916047P 20070504
- 国际公布： WO2008137770 20081113
- 主分类号： C07D401/14
- IPC分类号： C07D401/14 ; A61K31/506 ; A61P35/00 ; A61P37/00
摘要：
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of c-kit, PDGFRα and PDGFRβ kinases.
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