发明公开
- 专利标题： METHOD FOR ENHANCING IMMUNE RESPONSE WITH PEPTIDE
- 专利标题（中）： 用肽增强免疫应答的方法
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申请号： EP08751882.5申请日： 2008-04-18
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公开(公告)号： EP2149584A1公开(公告)日： 2010-02-03
- 发明人: MATSUDA, Junichi , KAMINAKA, Kazuyoshi , NOZAKI, Chikateru
- 申请人： Juridical Foundation The Chemo-Sero-Therapeutic Research Institute
- 申请人地址： 6-1, Ohkubo 1-chome Kumamoto-shi Kumamoto-ken 860-8568 JP
- 专利权人： Juridical Foundation The Chemo-Sero-Therapeutic Research Institute
- 当前专利权人： Juridical Foundation The Chemo-Sero-Therapeutic Research Institute
- 当前专利权人地址： 6-1, Ohkubo 1-chome Kumamoto-shi Kumamoto-ken 860-8568 JP
- 代理机构： Vossius & Partner
- 优先权： JP2007112060 20070420; JP2007279083 20071026
- 国际公布： WO2008133208 20081106
- 主分类号： C07K14/47
- IPC分类号： C07K14/47 ; A61K31/711 ; A61K39/00 ; A61K48/00 ; A61P25/28 ; A61K38/00
摘要：
An object of the present invention is to provide a safe and effective method for enhancing an immune response and a medicament for preventing or treating Alzheimer disease comprising amyloid β peptide that induces an enhanced immune response. An amyloid β peptide or a portion thereof with addition or insertion of cysteine and a method for enhancing an immune response using the peptide or a method for enhancing an immune response using the peptide together with an adjuvant. A medicament for preventing or treating Alzheimer disease comprising an amyloid β peptide or a portion thereof that induces an enhanced immune response. A DNA vaccine, that may have the same effect, comprising the gene encoding an amyloid β peptide or a portion thereof that induces an enhanced immune response with addition or insertion of cysteine.
公开/授权文献
- EP2149584B1 METHOD FOR ENHANCING IMMUNE RESPONSE WITH PEPTIDE 公开/授权日：2017-12-13
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