发明公开
- 专利标题: MODIFIED LECITHIN-CHOLESTEROL ACYLTRANSFERASE ENZYMES
- 专利标题(中): 改性磷脂,胆固醇酰基转移酶酶
-
申请号: EP08796592.7申请日: 2008-07-25
-
公开(公告)号: EP2181190A2公开(公告)日: 2010-05-05
- 发明人: ZHOU, Mingyue , BOONE, Thomas , MEININGER, David, Park , SCHWARTZ, Margrit , SHAN, Bei , SHEN, Wenyan
- 申请人: Amgen, Inc
- 申请人地址: Patent Operations, M/S 28-2-C One Amgen Center Drive Thousand Oaks, California 91320-1799 US
- 专利权人: Amgen, Inc
- 当前专利权人: Amgen, Inc
- 当前专利权人地址: Patent Operations, M/S 28-2-C One Amgen Center Drive Thousand Oaks, California 91320-1799 US
- 代理机构: Carr, Anne Marie
- 优先权: US952007P 20070726
- 国际公布: WO2009015314 20090129
- 主分类号: C12N9/10
- IPC分类号: C12N9/10 ; A61K38/45
摘要:
The invention provides compounds, pharmaceutical compositions and methods for treating atherosclerosis, coronary heart disease, thrombosis, and for decreasing or prevention of accumulation of cholesterol in a subject by modifying LCAT polypeptide.
公开/授权文献
- EP2181190B1 MODIFIED LECITHIN-CHOLESTEROL ACYLTRANSFERASE ENZYMES 公开/授权日:2014-01-08
信息查询