发明公开
EP2183217A2 GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF
审中-公开
糖皮质激素类似物，其制造，药物组合物及其使用方法
- 专利标题： GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF
- 专利标题（中）： 糖皮质激素类似物，其制造，药物组合物及其使用方法
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申请号： EP08826655.6申请日： 2008-07-21
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公开(公告)号： EP2183217A2公开(公告)日： 2010-05-12
- 发明人: KUZMICH, Daniel , REGAN, John R.
- 申请人： Boehringer Ingelheim International GmbH , Boehringer Ingelheim Pharma GmbH & Co. KG
- 申请人地址： Binger Strasse 173 55216 Ingelheim DE
- 专利权人： Boehringer Ingelheim International GmbH,Boehringer Ingelheim Pharma GmbH & Co. KG
- 当前专利权人： Boehringer Ingelheim International GmbH,Boehringer Ingelheim Pharma GmbH & Co. KG
- 当前专利权人地址： Binger Strasse 173 55216 Ingelheim DE
- 代理机构： Hammann, Heinz
- 优先权： US961858P 20070725
- 国际公布： WO2009015067 20090129
- 主分类号： C07D209/10
- IPC分类号： C07D209/10 ; C07D209/42 ; C07D211/04 ; C07D215/06 ; C07D217/04 ; C07D217/24 ; C07D231/12 ; C07D235/06 ; C07D307/79 ; C07D471/04 ; C07D295/13 ; C07D215/227 ; C07D215/233
摘要：
Compounds of Formula (I) wherein R
1 , R
2 , R
3 , R
4 , R
5 , R
6 , and R
7 are as defined herein, or a tautomer, prodrug, solvate, or salt thereof; pharmaceutical compositions containing such compounds, and methods of modulating the glucocorticoid receptor function and methods of treating disease-states or conditions mediated by the glucocorticoid receptor function or characterized by inflammatory, allergic, or proliferative processes in a patient using these compounds.
1 , R
2 , R
3 , R
4 , R
5 , R
6 , and R
7 are as defined herein, or a tautomer, prodrug, solvate, or salt thereof; pharmaceutical compositions containing such compounds, and methods of modulating the glucocorticoid receptor function and methods of treating disease-states or conditions mediated by the glucocorticoid receptor function or characterized by inflammatory, allergic, or proliferative processes in a patient using these compounds.
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