发明公开
EP2186893A1 PRODUCTION AND USE OF EPITOPE-TAGGED HEPATITIS C VIRUS PARTICLE
审中-公开
HERSTELLUNG UND VERWENDUNG EINES MIT EINEM EPITOP-TAG VERSEHENEN HEPATITIS-C-VIRUSPARTIKELS
- 专利标题： PRODUCTION AND USE OF EPITOPE-TAGGED HEPATITIS C VIRUS PARTICLE
- 专利标题（中）： HERSTELLUNG UND VERWENDUNG EINES MIT EINEM EPITOP-TAG VERSEHENEN HEPATITIS-C-VIRUSPARTIKELS
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申请号： EP08778269.4申请日： 2008-07-11
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公开(公告)号： EP2186893A1公开(公告)日： 2010-05-19
- 发明人: WAKITA, Takaji , SUZUKI, Tetsuro , TAKAHASHI, Hitoshi
- 申请人： JAPAN as represented by DIRECTOR GENERAL OF NATIONAL INSTITUTE OF INFECTIOUS DISEASES , Tokyo Metropolitan Organization for Medical Research , Toray Industries, Inc.
- 申请人地址： 23-1, Toyama-cho 1-chome Shinjuku-ku Tokyo 162-8640 JP
- 专利权人： JAPAN as represented by DIRECTOR GENERAL OF NATIONAL INSTITUTE OF INFECTIOUS DISEASES,Tokyo Metropolitan Organization for Medical Research,Toray Industries, Inc.
- 当前专利权人： JAPAN as represented by DIRECTOR GENERAL OF NATIONAL INSTITUTE OF INFECTIOUS DISEASES,Tokyo Metropolitan Organization for Medical Research,Toray Industries, Inc.
- 当前专利权人地址： 23-1, Toyama-cho 1-chome Shinjuku-ku Tokyo 162-8640 JP
- 代理机构： Kador, Ulrich
- 优先权： JP2007184587 20070713
- 国际公布： WO2009011413 20090122
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; A61K39/29 ; A61P1/16 ; A61P31/12 ; C07K16/08 ; C12N5/10 ; C12N7/00 ; C12N7/02
摘要：
This invention relates to a nucleic acid comprising a nucleic acid sequence encoding an epitope tag peptide in the hypervariable region 1 of the E2 protein of naturally occurring or chimeric hepatitis C virus (HCV) genome, an epitope-tagged HCV particle encoded by such nucleic acid, and a method for purifying the HCV particles at a high purity in a simple manner with the use of an anti-epitope tag antibody-immobilized support.
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