发明授权
EP2203430B1 N-PHENYL-DIOXO-HYDROPYRIMIDINES USEFUL AS HEPATITIS C VIRUS (HCV) INHIBITORS
有权
丙型肝炎病毒抑制剂（HCV）合适的N- PHENYLDIOXOHYDROPYRIMIDINE
- 专利标题： N-PHENYL-DIOXO-HYDROPYRIMIDINES USEFUL AS HEPATITIS C VIRUS (HCV) INHIBITORS
- 专利标题（中）： 丙型肝炎病毒抑制剂（HCV）合适的N- PHENYLDIOXOHYDROPYRIMIDINE
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申请号： EP08831558.5申请日： 2008-09-17
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公开(公告)号： EP2203430B1公开(公告)日： 2011-06-15
- 发明人: DONNER, Pamela L. , RANDOLPH, John T. , KRUEGER, Allan C. , BETEBENNER, David A. , HUTCHINSON, Douglas K. , LIU, Dachun , LIU, Yaya , LONGENECKER, Kenton L. , MARING, Clarence J. , PRATT, John K. , ROCKWAY, Todd W. , STEWART, Kent D. , WAGNER, Rolf , BARNES, David M. , CHEN, Shuang , FRANCZYK II, Thaddeus S. , GAO, Yi , HAIGHT, Anthony R. , HENGEVELD, John E. , HENRY, Rodger F. , KOTECKI, Brian J. , LOU, Xiaochun , ZHANG, Geoff G. Z.
- 申请人： Abbott Laboratories
- 申请人地址： 100 Abbott Park Road Abbott Park, Illinois 60064 US
- 专利权人： Abbott Laboratories
- 当前专利权人： Abbott Laboratories
- 当前专利权人地址： 100 Abbott Park Road Abbott Park, Illinois 60064 US
- 代理机构： Wright, Robert Gordon McRae
- 优先权： US972887P 20070917; US96794P 20080913
- 国际公布： WO2009039135 20090326
- 主分类号： C07D239/22
- IPC分类号： C07D239/22 ; C07D239/54 ; C07D401/10 ; C07D403/10 ; C07D405/10 ; C07D409/10 ; C07D413/10 ; C07D239/553 ; A61K31/513 ; A61K31/506 ; A61P31/14
摘要：
This invention relates to: (a) compounds and salts thereof that, inter alia, inhibit HCV; (b) intermediates useful for the preparation of such compounds and salts; (c) compositions comprising such compounds and salts; (d) methods for preparing such intermediates, compounds, salts, and compositions; (e) methods of use of such compounds, salts, and compositions; and (f) kits comprising such compounds, salts, and compositions. The compounds are usefull in the treatment of hepatitis C and are of the following general structure: Formula (I)
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