发明公开
EP2205259A1 METHOD OF REGULATING THE TH17 PATHWAY AND ITS ASSOCIATED METABOLIC IMPACT
有权
MPM(ABLE MALLE蛋白质基质)FOR USE IN肥胖,胰岛素抵抗,2型糖尿病,自身免疫性疾病,高血压和高脂血症的治疗
- 专利标题: METHOD OF REGULATING THE TH17 PATHWAY AND ITS ASSOCIATED METABOLIC IMPACT
- 专利标题(中): MPM(ABLE MALLE蛋白质基质)FOR USE IN肥胖,胰岛素抵抗,2型糖尿病,自身免疫性疾病,高血压和高脂血症的治疗
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申请号: EP08800421.3申请日: 2008-10-02
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公开(公告)号: EP2205259A1公开(公告)日: 2010-07-14
- 发明人: BEAULIEU, Josée , LAPOINTE, Jean-François , DUPONT, Claude , LEMIEUX, Pierre , SIMARD, Eric , TROTTIER, Eric
- 申请人: Institut National de la Recherche Scientifique
- 申请人地址: 490, de la Couronne Québec G1K 9A9 CA
- 专利权人: Institut National de la Recherche Scientifique
- 当前专利权人: Institut National de la Recherche Scientifique
- 当前专利权人地址: 490, de la Couronne Québec G1K 9A9 CA
- 代理机构: Faivre Petit, Frédérique
- 优先权: US976983P 20071002
- 国际公布: WO2009043171 20090409
- 主分类号: A61K38/02
- IPC分类号: A61K38/02 ; A61P29/00 ; A61P37/02 ; A61P37/06
摘要:
It is disclosed a method of immunomodulating an immune response in a subject comprising administering to a subject a malleable protein matrix (MPM), from fermented whey, in an amount effective to modulate the biological activity of Th17 cells, and its associated metabolic pathway, for a preventative or a therapeutic purpose of a variety of health applications in the field of immunity or obesity related diseases.
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