发明公开
- 专利标题： 2-MORPHOLINYLPURINES AS INHIBITORS OF PI3K
- 专利标题（中）： 2-吗啉基嘌呤作为PI3K的抑制剂
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申请号： EP08835471.7申请日： 2008-10-03
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公开(公告)号： EP2209785A1公开(公告)日： 2010-07-28
- 发明人: NAGARAJ, Harish, Kumar, Mysore , CHEN, Dizhong , POULSEN, Anders , WILLIAMS, Meredith
- 申请人： S*BIO Pte Ltd
- 申请人地址： 1 Science Park Road 05-09 The Capricorn Singapore Science Park II Singapore 117528 SG
- 专利权人： S*BIO Pte Ltd
- 当前专利权人： S*BIO Pte Ltd
- 当前专利权人地址： 1 Science Park Road 05-09 The Capricorn Singapore Science Park II Singapore 117528 SG
- 代理机构： Schwahn, Hartmut
- 优先权： US977720P 20071005; US76304 20080627
- 国际公布： WO2009045174 20090409
- 主分类号： C07D473/32
- IPC分类号： C07D473/32 ; A61K31/52 ; A61P35/00
摘要：
The present invention relates to purine compounds that are useful as kinase inhibitors. More particularly, the present invention relates to purine compounds, methods for their preparation, pharmaceutical compositions containing these compounds and uses of these compounds in the treatment of proliferative disorders. These compounds may be useful as medicaments for the treatment of a number of proliferative disorders including tumours and cancers as well as other disorders or conditions related to or associated with mTOR kinases.
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