发明公开
EP2213652A1 Stilbene derivatives and their use for binding and imaging amyloid plaques
有权
Stilbenderivate和ihre Verwendung zum Binden und Abbilden von Amyloidplaques
- 专利标题: Stilbene derivatives and their use for binding and imaging amyloid plaques
- 专利标题(中): Stilbenderivate和ihre Verwendung zum Binden und Abbilden von Amyloidplaques
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申请号: EP10161604.3申请日: 2005-12-19
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公开(公告)号: EP2213652A1公开(公告)日: 2010-08-04
- 发明人: Kung, Hank F. , Kung, Mei-Ping , Zhuang, Zhi-Ping
- 申请人: The Trustees of The University of Pennsylvania
- 申请人地址: 3160 Chestnut Street, Suite 200 Philadelphia, Pennsylvania 19104-6283 US
- 专利权人: The Trustees of The University of Pennsylvania
- 当前专利权人: The Trustees of The University of Pennsylvania
- 当前专利权人地址: 3160 Chestnut Street, Suite 200 Philadelphia, Pennsylvania 19104-6283 US
- 代理机构: Dörries, Hans Ulrich
- 优先权: US636696P 20041217; US686395P 20050602
- 主分类号: C07C217/80
- IPC分类号: C07C217/80 ; A61K31/135
摘要:
This invention relates to a method of imaging amyloid deposits and to labeled compounds, and methods of making labeled compounds useful in imaging amyloid deposits. This invention also relates to compounds, and methods of making compounds for inhibiting the aggregation of amyloid proteins to form amyloid deposits, and a method of delivering a therapeutic agent to amyloid deposits.
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