发明公开
EP2215091A2 SUBSTITUTED DIHYDROPTERIDIN-6-ONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS
有权
取代的二氢蝶啶-6-酮衍生物，其制备及其作为激酶抑制剂
- 专利标题： SUBSTITUTED DIHYDROPTERIDIN-6-ONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS
- 专利标题（中）： 取代的二氢蝶啶-6-酮衍生物，其制备及其作为激酶抑制剂
-
申请号： EP08856914.0申请日： 2008-11-26
-
公开(公告)号： EP2215091A2公开(公告)日： 2010-08-11
- 发明人: CARUSO, Michele , BERIA, Italo , BRASCA, Maria, Gabriella , POSTERI, Helena , FACHIN, Gabriele
- 申请人： Nerviano Medical Sciences S.r.l.
- 申请人地址： Viale Pasteur, 10 20014 Nerviano (MI) IT
- 专利权人： Nerviano Medical Sciences S.r.l.
- 当前专利权人： Nerviano Medical Sciences S.r.l.
- 当前专利权人地址： Viale Pasteur, 10 20014 Nerviano (MI) IT
- 优先权： EP07122297 20071204
- 国际公布： WO2009071480 20090611
- 主分类号： C07D475/00
- IPC分类号： C07D475/00 ; A61K31/519 ; A61P35/00 ; A61P31/00
摘要：
Dihydropteridin-6-one derivatives of formula (I) as defined in the specification, and pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer.
公开/授权文献
信息查询
IPC分类:
| C | 化学；冶金 |
| C07 | 有机化学 |
| C07D | 杂环化合物（高分子化合物入C08） |
| C07D475/00 | 含蝶啶环系的杂环化合物 |
