发明公开
- 专利标题: DURCH POLYMERISATION HÄRTBARE ZUSAMMENSETZUNG ZUR HERSTELLUNG BIOLOGISCH ABBAUBARER, BIOVERTRÄGLICHER, VERNETZTER POLYMERE AUF BASIS VON POLYVINYLALKOHOL
- 专利标题(英): Composition that can be cured by polymerisation for the production of biodegradable, biocompatible, cross-linkable polymers on the basis of polyvinyl alcohol
- 专利标题(中): 聚合固化性组合物用于生产生物降解的生物相容性,交联聚合物基于聚乙烯醇
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申请号: EP08852256.0申请日: 2008-11-21
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公开(公告)号: EP2219697A2公开(公告)日: 2010-08-25
- 发明人: LISKA, Robert , STAMPFL, Jürgen , VARGA, Franz , GRUBER, Heinrich , BAUDIS, Stefan , HELLER, Christian , SCHUSTER, Monika , BERGMEISTER, Helga , WEIGEL, Günter , DWORAK, Claudia
- 申请人: Technische Universität Wien
- 申请人地址: Karlsplatz 13 1040 Wien AT
- 专利权人: Technische Universität Wien
- 当前专利权人: Technische Universität Wien
- 当前专利权人地址: Karlsplatz 13 1040 Wien AT
- 代理机构: Ellmeyer, Wolfgang
- 优先权: AT19032007 20071123; AT4612008 20080325
- 国际公布: WO2009065162 20090528
- 主分类号: A61L27/56
- IPC分类号: A61L27/56 ; C08F18/14
摘要:
The invention relates to a polymerisable composition for the production of biodegradable, biocompatible, cross-linked polymers on the basis of polyvinyl alcohol, comprising: 5-100 % by weight vinyl ester monomer(s) of general formula (I), (II) or (III), in which X represents oxygen, sulphur, nitrogen or phosphor, n = 1-1000, at least 20% of n ≥2, R1 is selected from hydrogen, unbranched, branched or cyclic, saturated or unsaturated, n-valent hydrocarbon groups comprising 1-30 carbon atoms, which optionally have heteroatoms and are optionally substituted by substituents selected from -OH, -COOH, -CN, -CHO and =O and from n-valent groups of biodegradable, biocompatible oligomers and polymers, m = 1-5, R2 is selected from hydrogen, -OH, =O and the options for R1 and R3 is selected from hydrogen, -OH and the options for R1; 0-50 % by weight of ethylenically unsaturated comonomers; 0-10 % by weight of polymerisation initiator(s); and 0-95 % by weight of solvents.
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