发明公开
EP2226636A1 Cancer diagnosis and treatment using anti-robo1 antibody
有权
Krebsdiagnose und Behandlung unter Verwendung eines anti-Robo1-Antikörper
- 专利标题： Cancer diagnosis and treatment using anti-robo1 antibody
- 专利标题（中）： Krebsdiagnose und Behandlung unter Verwendung eines anti-Robo1-Antikörper
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申请号： EP10003419.8申请日： 2005-03-31
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公开(公告)号： EP2226636A1公开(公告)日： 2010-09-08
- 发明人: Aburatani, Hiroyuki , Hippo, Yoshitaka , Watanabe, Akira , Fukayama, Masashi , Ito, Yukio , Arai, Masahiro , Ito, Hirotaka , Ohtomo, Toshihiko , Funahashi, Shin-ichi , Kinoshita, Yasuko
- 申请人： Aburatani, Hiroyuki , Perseus Proteomics Inc. , Chugai Seiyaku Kabushiki Kaisha
- 申请人地址： 3-30-16 Kichijoji-Minami-cho Musashino-shi, Tokyo 180-0003 JP
- 专利权人： Aburatani, Hiroyuki,Perseus Proteomics Inc.,Chugai Seiyaku Kabushiki Kaisha
- 当前专利权人： Aburatani, Hiroyuki,Perseus Proteomics Inc.,Chugai Seiyaku Kabushiki Kaisha
- 当前专利权人地址： 3-30-16 Kichijoji-Minami-cho Musashino-shi, Tokyo 180-0003 JP
- 代理机构： Woods, Geoffrey Corlett
- 优先权： JP2004102862 20040331; JP2004227899 20040804; JP2005004024 20050111
- 主分类号： G01N33/574
- IPC分类号： G01N33/574 ; C12N15/02 ; C12N15/09
摘要：
A method for diagnosing cancer comprising detecting ROBO1 protein is disclosed. In addition, a method for treating a disease caused by abnormal cell growth comprising administrating an antibody that binds to ROBO1, as well as a pharmaceutical composition, a cell growth inhibitor and an anticancer agent comprising an antibody that binds to ROBO1 as an active ingredient are disclosed. Further, a method for inducing cell damages in a ROBO1 expressing cell and a method for inhibiting the growth of a ROBO1 expressing cell by bringing a ROBO1 expressing cell into contact with an antibody that binds to ROBO1, are disclosed. Furthermore, a method for monitoring progression of hepatitis by detecting ROBO1 protein is disclosed.
公开/授权文献
- EP2226636B1 Cancer diagnosis and treatment using anti-robo1 antibody 公开/授权日：2012-03-21
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