发明公开
EP2227475A1 ISOXAZOLOPYRIDINE DERIVATIVES FOR USE IN THE TREATMENT OF HIF-MEDIATED CONDITIONS
有权
ISOXAZOLOPYRIDINDERIVATE FOR USE IN HIF分别赋以处理交换式莱顿
- 专利标题： ISOXAZOLOPYRIDINE DERIVATIVES FOR USE IN THE TREATMENT OF HIF-MEDIATED CONDITIONS
- 专利标题（中）： ISOXAZOLOPYRIDINDERIVATE FOR USE IN HIF分别赋以处理交换式莱顿
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申请号： EP08857227.6申请日： 2008-12-02
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公开(公告)号： EP2227475A1公开(公告)日： 2010-09-15
- 发明人: AREND, Michael P. , CHENG, Heng , FLIPPIN, Lee A. , NG, Danny , TURTLE, Eric , WU, Min
- 申请人： Fibrogen, Inc.
- 申请人地址： 409 Illinois Street San Francisco, CA 94158 US
- 专利权人： Fibrogen, Inc.
- 当前专利权人： Fibrogen, Inc.
- 当前专利权人地址： 409 Illinois Street San Francisco, CA 94158 US
- 代理机构： Goodfellow, Hugh Robin
- 优先权： US991948P 20071203
- 国际公布： WO2009073669 20090611
- 主分类号： C07D498/04
- IPC分类号： C07D498/04 ; A61K31/437 ; A61P7/00 ; A61P9/00
摘要：
The present invention relates to novel compounds of formula (I) capable of modulating the stability and/or activity of hypoxia inducible factor (HIF) by inhibiting the activity of at least one HIF hydroxylase enzyme.
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