发明公开
- 专利标题： MONOSEBACATE OF PYRAZOLE DERIVATIVE
- 专利标题（中）： 吡唑衍生物的单糖化物
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申请号： EP08867231.6申请日： 2008-12-24
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公开(公告)号： EP2228378A1公开(公告)日： 2010-09-15
- 发明人: TAKEUCHI, Hideki , TSURU, Eiji
- 申请人： Kissei Pharmaceutical Co., Ltd.
- 申请人地址： 19-48, Yoshino Matsumoto-shi Nagano 399-8710 JP
- 专利权人： Kissei Pharmaceutical Co., Ltd.
- 当前专利权人： Kissei Pharmaceutical Co., Ltd.
- 当前专利权人地址： 19-48, Yoshino Matsumoto-shi Nagano 399-8710 JP
- 代理机构： Hayes, Adrian Chetwynd
- 优先权： JP2007337985 20071227
- 国际公布： WO2009084531 20090709
- 主分类号： C07H17/02
- IPC分类号： C07H17/02 ; A61K31/7056 ; A61P3/00 ; A61P3/04 ; A61P3/06 ; A61P3/08 ; A61P3/10 ; A61P7/10 ; A61P9/04 ; A61P9/10 ; A61P9/12 ; A61P19/06 ; A61P43/00
摘要：
The present invention provides a novel form of 3-(3-{4-[3-(β-D-gluco-pyranosyloxy)-5-isopropyl-1H-pyrazol-4-ylmethyl]-3-methylphenoxy}propylamino)-2,2-dimethylpropionamide with improved storage stability. Since bis[3-(3-{4-[3-( - D-glucopyranosyloxy)-5-isopropyl-1H-pyrazol-4-ylmethyl]-3-methylphenoxy}pr opylamino)-2,2-dimethylpropionamide] monosebacate has extremely excellent storage stability, it is useful as a drug substance. Furthermore, it shows an extremely good crystalline property and can be purified by a convenient method, and therefore is suitable for the industrial preparation.
公开/授权文献
- EP2228378B1 MONOSEBACATE OF PYRAZOLE DERIVATIVE 公开/授权日：2015-09-09
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