发明公开
- 专利标题： GAMMA SECRETASE MODULATORS
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申请号： EP08859465.0申请日： 2008-12-12
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公开(公告)号： EP2231602A1公开(公告)日： 2010-09-29
- 发明人: HITCHCOCK, Stephen , CHEN, Jian J. , NCUBE, Mqhele , NIXEY, Thomas , AMEGADZIE, Albert , KUNZ, Roxanne , QIAN, Wenyuan , CHEN, Ning , TEGLEY, Christopher M. , DEMORIN, Frenel , YUAN, Chester Chenguang , LIU, Qingyian , ZHU, Jiawang , PETERKIN, Tanya , ADAMS, Jeffrey A. , HU, Essa , CHAVEZ, JR., Frank
- 申请人： Amgen, Inc
- 申请人地址： One Amgen Center Drive Thousand Oaks, California 91320-1799 US
- 专利权人： Amgen, Inc
- 当前专利权人： Amgen, Inc
- 当前专利权人地址： One Amgen Center Drive Thousand Oaks, California 91320-1799 US
- 代理机构： Sendrowski, Heiko
- 优先权： US7486P 20071213
- 国际公布： WO2009075874 20090618
- 主分类号： C07D213/40
- IPC分类号： C07D213/40 ; C07D401/12 ; C07D401/14 ; C07D405/12 ; C07D413/12 ; A61K31/00 ; A61P25/28
摘要：
The present invention provides compounds that are gamma secretase modulators and are therefore useful for the treatment of diseases treatable by modulation of gamma secretase such as Alzheimer's disease. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.
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