Control of uplink transmit power for a first mobile station operating with scheduled uplink data transmissions. A change in uplink scheduled status for the first mobile station is detected (301). Filtering of uplink interference measurements for the first mobile station is adapted (302) to account for the detected change in uplink scheduled status for the first mobile station. Alternatively a change in uplink scheduled status for a second mobile station is detected and a current filtering state for filtering of uplink interference measurements for the first mobile station is adjusted by applying an estimated expected change in interference associated with the detected change. A signal quality for uplink transmissions from the first mobile station is determined (303) based on measurements of received signal strength from the mobile station and the filtered uplink interference measurements. An uplink transmit power command is generated (304) for the first mobile station based on a comparison of the estimated signal quality to a signal quality target.