发明公开
EP2246702A1 BIOSENSING METHOD USING COATED MAGNETIC MICROPARTICLES AND BIOSENSING DEVICE TO BE USED IN THE METHOD
有权
生物传感方法使用涂磁微颗粒中的过程;适用生物传感器件
- 专利标题： BIOSENSING METHOD USING COATED MAGNETIC MICROPARTICLES AND BIOSENSING DEVICE TO BE USED IN THE METHOD
- 专利标题（中）： 生物传感方法使用涂磁微颗粒中的过程;适用生物传感器件
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申请号： EP08857449.6申请日： 2008-12-01
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公开(公告)号： EP2246702A1公开(公告)日： 2010-11-03
- 发明人: HANDA, Hiroshi , ABE, Masanori , HATAKEYAMA, Mamoru , SAKAMOTO, Satoshi , NISHIO, Kosuke , MOCHIZUKI, Yusuke
- 申请人： Tokyo Institute of Technology
- 申请人地址： 2-12-1, Ookayama Meguro-ku Tokyo 152-0033 JP
- 专利权人： Tokyo Institute of Technology
- 当前专利权人： Tokyo Institute of Technology
- 当前专利权人地址： 2-12-1, Ookayama Meguro-ku Tokyo 152-0033 JP
- 代理机构： Manitz, Finsterwald & Partner GbR
- 优先权： JP2007311860 20071203
- 国际公布： WO2009072457 20090611
- 主分类号： G01N33/543
- IPC分类号： G01N33/543 ; G01N5/02 ; G01N21/27 ; G01N33/553
摘要：
An object of the present invention is to provide a novel biosensing method as the novel application development of the magnetic particles in the biosensing. In an affinity reaction of biosensing, ligands are immobilized to magnetic fine particles and the magnetic fine particles are forced to reaction fields of the affinity reaction by magnetic guiding so as to bring the affinity reaction, which is the velocity controlling factor in the sensing, to high rates. According to the present invention, coated magnetic fine particles with having both of the high dispersion performance and high magnetic responsibility as the above described magnetic fine particles and the affinity reaction occurs quickly and in high density such that the present invention makes it possible to obtain relatively large signals within significantly short time duration when compared to the conventional art.
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