发明公开
EP2254888A1 NOVEL AMINOPYRIDINE DERIVATIVES HAVING AURORA A SELECTIVE INHIBITORY ACTION
有权
具有选择性抑制作用的新型氨基吡啶衍生物
- 专利标题: NOVEL AMINOPYRIDINE DERIVATIVES HAVING AURORA A SELECTIVE INHIBITORY ACTION
- 专利标题(中): 具有选择性抑制作用的新型氨基吡啶衍生物
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申请号: EP09711943.2申请日: 2009-02-18
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公开(公告)号: EP2254888A1公开(公告)日: 2010-12-01
- 发明人: KATO, Tetsuya , KAWANISHI, Nobuhiko , MITA, Takashi , NONOSHITA, Katsumasa , OHKUBO, Mitsuru
- 申请人: Banyu Pharmaceutical Co., Ltd.
- 申请人地址: Kitanomaru Square 1-13-12 Kudankita Chiyoda-ku Tokyo 102-8667 JP
- 专利权人: Banyu Pharmaceutical Co., Ltd.
- 当前专利权人: Banyu Pharmaceutical Co., Ltd.
- 当前专利权人地址: Kitanomaru Square 1-13-12 Kudankita Chiyoda-ku Tokyo 102-8667 JP
- 代理机构: Hussain, Deeba
- 优先权: US66724 20080222
- 国际公布: WO2009104802 20090827
- 主分类号: C07D417/14
- IPC分类号: C07D417/14 ; A61K31/4545 ; A61K31/506 ; A61P35/00 ; A61P41/00 ; C07D401/14 ; C07D413/14
摘要:
The present invention relates to a compound of formula I:wherein: R
1 is a hydrogen atom, F, CN, etc.; R
2 is CO, SO
2 , etc.; R
3 is a phenyl which may be substituted; X
1 , X
2 , and X
3 each independently CH, N, etc. provided, however, that among X
1 , X
2 and X
3 , the number of nitrogen is 0 or 1; W is the following residue:wherein: W
1 , W
2 , and W
3 each independently CH, N, etc.,or a pharmaceutically acceptable salt or ester thereof.
1 is a hydrogen atom, F, CN, etc.; R
2 is CO, SO
2 , etc.; R
3 is a phenyl which may be substituted; X
1 , X
2 , and X
3 each independently CH, N, etc. provided, however, that among X
1 , X
2 and X
3 , the number of nitrogen is 0 or 1; W is the following residue:wherein: W
1 , W
2 , and W
3 each independently CH, N, etc.,or a pharmaceutically acceptable salt or ester thereof.
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