发明公开
- 专利标题： PYRAZOLE [3, 4-B]PYRIDINE RAF INHIBITORS
- 专利标题（中）： - 吡唑并[3,4-b]吡啶RAF抑制剂
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申请号： EP09718306.5申请日： 2009-02-27
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公开(公告)号： EP2265610A1公开(公告)日： 2010-12-29
- 发明人: AHRENDT, Kateri A. , BUCKMELTER, Alexandre J. , DE MEESE, Jason , GRINA, Jonas , HANSEN, Joshua D. , LAIRD, Ellen R. , LUNGHOFER, Paul , MORENO, David , NEWHOUSE, Brad , REN, Li , SEO, Jeongbeob , TIAN, Hongqi , WENGLOWSKY, Steven Mark , FENG, Bainian , GUNZNER, Janet , MALESKY, Kim , MATHIEU, Simon , RUDOLPH, Joachim , WEN, Zhaoyang , YOUNG, Wendy B.
- 申请人： Array Biopharma, Inc. , Genentech, Inc.
- 申请人地址： 3200 Walnut Street Boulder, CO 80301 US
- 专利权人： Array Biopharma, Inc.,Genentech, Inc.
- 当前专利权人： Array Biopharma, Inc.,Genentech, Inc.
- 当前专利权人地址： 3200 Walnut Street Boulder, CO 80301 US
- 代理机构： Bailey, Sam Rogerson
- 优先权： US32813 20080229
- 国际公布： WO2009111279 20090911
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; C07C311/08 ; A61K31/437 ; A61P13/12 ; A61P35/00
摘要：
Compounds of Formula I are useful for inhibition of Raf kinases. Methods of using compounds of Formula I and stereoisomers, tautomers, prodrugs and pharmaceutically acceptable salts thereof, for in vitro,
in situ, and
in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.
in situ, and
in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.
公开/授权文献
- EP2265610B1 PYRAZOLE [3, 4-B]PYRIDINE RAF INHIBITORS 公开/授权日：2012-12-12
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