发明公开
- 专利标题: BUTENAFINE HYDROCHLORIDE-CONTAINING AQUEOUS PATCH
- 专利标题(中): 含苯丁胺盐酸盐的水性贴剂
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申请号: EP09730460.4申请日: 2009-03-24
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公开(公告)号: EP2266553A1公开(公告)日: 2010-12-29
- 发明人: KAMAKURA, Takashi , HOSHIKAWA, Takefumi , INAMOTO, Yukiko , TANIGAWA, Kayo
- 申请人: Teikoku Seiyaku Co., Ltd.
- 申请人地址: 567 Sanbonmatsu Higashikagawa-shi, Kagawa 769-2695 JP
- 专利权人: Teikoku Seiyaku Co., Ltd.
- 当前专利权人: Teikoku Seiyaku Co., Ltd.
- 当前专利权人地址: 567 Sanbonmatsu Higashikagawa-shi, Kagawa 769-2695 JP
- 代理机构: Albrecht, Thomas
- 优先权: JP2008100041 20080408
- 国际公布: WO2009125667 20091015
- 主分类号: A61K31/137
- IPC分类号: A61K31/137 ; A61K9/70 ; A61K47/10 ; A61K47/14 ; A61P31/10
摘要:
An aqueous patch is provided which has excellent storage stability and provides excellent retention of butenafine hydrochloride blended therein onto the application sites such as skin and nails and is highly therapeutic. The butenafine hydrochloride-containing aqueous patch includes butenafine hydrochloride, glycol salicylate, and propylene glycol in a hydrogel paste. Specifically, the butenafine hydrochloride-containing aqueous patch is produced by dissolving butenafine hydrochloride in a mixed solution of glycol salicylate and propylene glycol and dispersing the resulting solution in a hydrogel is provided. In particular, in the butenafine hydrochloride-containing aqueous patch, glycol salicylate and propylene glycol are mixed in a ratio of 1:2 to 1:30.
公开/授权文献
- EP2266553B1 BUTENAFINE HYDROCHLORIDE-CONTAINING AQUEOUS PATCH 公开/授权日:2017-01-25
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