发明公开
EP2271648A1 ISOXAZOLINE LINKED PYRROLO [2,1-C][1,4]BENZODIAZEPINE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND THE PROCESS FOR PREPARATTION THEREOF
有权
异恶唑啉LINKED吡咯并[2,1-C] [1,4] BENZODIAZEPINHYBRIDE作为潜在抗癌剂和PROCESS FOR THEIR
- 专利标题： ISOXAZOLINE LINKED PYRROLO [2,1-C][1,4]BENZODIAZEPINE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND THE PROCESS FOR PREPARATTION THEREOF
- 专利标题（中）： 异恶唑啉LINKED吡咯并[2,1-C] [1,4] BENZODIAZEPINHYBRIDE作为潜在抗癌剂和PROCESS FOR THEIR
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申请号： EP08873662.4申请日： 2008-10-31
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公开(公告)号： EP2271648A1公开(公告)日： 2011-01-12
- 发明人: KAMAL, Ahmed , REDDY, Jonnala, Surendranadha , DASTAGIRI, Dudekula , BHARATHI, Earla, Vijaya
- 申请人： Council of Scientific & Industrial Research
- 申请人地址： Anusandhan Bhawan, 2 Rafi Marg New Delhi 110 001 IN
- 专利权人： Council of Scientific & Industrial Research
- 当前专利权人： Council of Scientific & Industrial Research
- 当前专利权人地址： Anusandhan Bhawan, 2 Rafi Marg New Delhi 110 001 IN
- 代理机构： Towler, Philip Dean
- 优先权： INDE07852008 20080326
- 国际公布： WO2009118748 20091001
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; A61K31/5517 ; A61P35/00
摘要：
The present invention provides compounds of general formula (5a-d) and (9a-h) useful as potential antitumour agents against human cancer cell lines. The present invention also provides a process for the preparation of pyrrolo [2,1-
c ][1,4]benzodiazepine hybrids of general formula (5a-d) and (9a-h).
c ][1,4]benzodiazepine hybrids of general formula (5a-d) and (9a-h).
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