- 专利标题： Derivatives of 4-piperazin-1-yl-4-benzo[b]thiophene suitable for the treatment of CNS disorders
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申请号： EP10188683.6申请日： 2006-08-31
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公开(公告)号： EP2287162B1公开(公告)日： 2012-05-09
- 发明人: Yamashita, Hiroshi , Kuroda, Hideaki , Takahashi, Haruka , Fukushima, Tae
- 申请人： Otsuka Pharmaceutical Co., Ltd.
- 申请人地址： 2-9 Kanda-Tsukasa-machi Chiyoda-ku Tokyo 101-8535 JP
- 专利权人： Otsuka Pharmaceutical Co., Ltd.
- 当前专利权人： Otsuka Pharmaceutical Co., Ltd.
- 当前专利权人地址： 2-9 Kanda-Tsukasa-machi Chiyoda-ku Tokyo 101-8535 JP
- 代理机构： HOFFMANN EITLE
- 优先权： JP2005251055 20050831
- 主分类号： C07D409/12
- IPC分类号： C07D409/12 ; C07D333/54 ; C07D407/12 ; C07D413/12 ; C07D417/12 ; A61K31/559 ; A61P25/00
摘要：
A heterocyclic compound or a salt thereof represented by the formula (I): where R 2 represents a hydrogen atom or a lower alkyl group; A represents a lower alkylene group or a lower alkenylene group; and R 1 represents a cylo C3-C8 alkyl group. The compound of the present invention has a wide treatment spectrum for mental disorders including central nervous system disorders, no side effects and high safety.
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