发明公开
- 专利标题: TETRAZOLE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS
- 专利标题(中): 四唑ALS食欲素受体拮抗剂
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申请号: EP09762141.1申请日: 2009-06-10
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公开(公告)号: EP2288603A1公开(公告)日: 2011-03-02
- 发明人: AISSAOUI, Hamed , BOSS, Christoph , BROTSCHI, Christine , GATFIELD, John , KOBERSTEIN, Ralf , SIEGRIST, Romain , SIFFERLEN, Thierry , WILLIAMS, Jodi T.
- 申请人: Actelion Pharmaceuticals Ltd.
- 申请人地址: Gewerbestrasse 16 4123 Allschwil CH
- 专利权人: Actelion Pharmaceuticals Ltd.
- 当前专利权人: Actelion Pharmaceuticals Ltd.
- 当前专利权人地址: Gewerbestrasse 16 4123 Allschwil CH
- 代理机构: Velker, Jörg
- 优先权: PCT/IB2008/052297 20080611
- 国际公布: WO2009150614 20091217
- 主分类号: C07D401/14
- IPC分类号: C07D401/14 ; C07D403/12 ; C07D405/14 ; C07D409/14 ; A61P25/00 ; A61P3/10
摘要:
The invention relates to tetrazole compounds of formula (I) wherein X, Y, Z, R
1 , R
2 and R
3 are as described in the description; to pharmaceutically acceptable salts thereof, and to the use of such compounds use as medicaments, especially as orexin receptor antagonists.
1 , R
2 and R
3 are as described in the description; to pharmaceutically acceptable salts thereof, and to the use of such compounds use as medicaments, especially as orexin receptor antagonists.
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