发明公开
- 专利标题： NOVEL HETEROARYL CARBOXAMIDE DERIVATIVES
- 专利标题（中）： 新型杂芳酰基甲酰胺衍生物
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申请号： EP09765762.1申请日： 2009-06-08
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公开(公告)号： EP2297137A1公开(公告)日： 2011-03-23
- 发明人: ADAM, Jean-Michel , AEBI, Johannes , BINGGELI, Alfred , GREEN, Luke , HARTMANN, Guido , MAERKI, Hans P. , MATTEI, Patrizio , RICKLIN, Fabienne , ROCHE, Olivier
- 申请人： F. Hoffmann-La Roche AG
- 申请人地址： Grenzacherstrasse 124 4070 Basel CH
- 专利权人： F. Hoffmann-La Roche AG
- 当前专利权人： F. Hoffmann-La Roche AG
- 当前专利权人地址： Grenzacherstrasse 124 4070 Basel CH
- 代理机构： Salud, Carlos E.
- 优先权： EP08158499 20080618
- 国际公布： WO2009153182 20091223
- 主分类号： C07D401/14
- IPC分类号： C07D401/14 ; C07D471/04 ; A61K31/437 ; A61K31/4468 ; A61P9/00 ; A61P25/00 ; A61P19/02 ; A61P1/00
摘要：
The invention is concerned with novel heteroaryl carboxamide derivatives of Formula (I), wherein (II), m, X, Y, R
1 , R
2 , R
3 and R
4 are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds are antagonists of CCR-2 receptor, CCR-5 receptor and/or CCR-3 receptor and can be used as medicaments.
1 , R
2 , R
3 and R
4 are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds are antagonists of CCR-2 receptor, CCR-5 receptor and/or CCR-3 receptor and can be used as medicaments.
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