发明公开
- 专利标题： ORGANIC COMPOUNDS
- 专利标题（中）： 吡嗪ALS阻断上皮钠通道
-
申请号： EP09761700.5申请日： 2009-06-08
-
公开(公告)号： EP2300010A2公开(公告)日： 2011-03-30
- 发明人: COLLINGWOOD, Stephen Paul , DEVEREUX, Nicholas James , HOWSHAM, Catherine , HUNT, Peter , HUNT, Thomas Anthony
- 申请人： Novartis AG
- 申请人地址： Lichtstrasse 35 4056 Basel CH
- 专利权人： Novartis AG
- 当前专利权人： Novartis AG
- 当前专利权人地址： Lichtstrasse 35 4056 Basel CH
- 代理机构： Mueller, Philippe
- 优先权： EP08157980 20080610
- 国际公布： WO2009150137 20091217
- 主分类号： A61K31/497
- IPC分类号： A61K31/497 ; A61P11/00
摘要：
A compound of Formula (I) or a hydrate or solvate thereof, where R
1 , R
2 , R
3 , R
4 , R
5 , R
6 , R
7 , R
8 , R
9 and R
10 have the meanings as indicated in the specification, is useful for treating diseases which respond to the blockade of the epithelial sodium channel. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
1 , R
2 , R
3 , R
4 , R
5 , R
6 , R
7 , R
8 , R
9 and R
10 have the meanings as indicated in the specification, is useful for treating diseases which respond to the blockade of the epithelial sodium channel. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
公开/授权文献
- EP2300010B1 PYRAZINE DERIVATIVES AS EPITHELIAL SODIUM CHANNEL BLOCKERS 公开/授权日：2015-03-04
信息查询
IPC分类:
