发明授权
- 专利标题: SCLEROSTIN EPITOPES
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申请号: EP10014373.4申请日: 2006-04-28
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公开(公告)号: EP2301961B1公开(公告)日: 2017-02-22
- 发明人: Lu, Hsieng Sen , Paszty, Christopher , Robinson, Martyn Kim , Henry, Alistair James , Hoffmann, Kelly Sue , Latham, John , Lawson, Alastair , Winkler, David , Winters, Aaron George
- 申请人: Amgen Inc.
- 申请人地址: One Amgen Center Drive Thousand Oaks, California 91320-1799 US
- 专利权人: Amgen Inc.
- 当前专利权人: Amgen Inc.
- 当前专利权人地址: One Amgen Center Drive Thousand Oaks, California 91320-1799 US
- 代理机构: Campbell, Patrick John Henry
- 优先权: US677583P 20050503; US776847P 20060224; US782244P 20060313; US792645P 20060417; US410540 20060425
- 主分类号: A61K39/00
- IPC分类号: A61K39/00 ; C07K16/18 ; C07K16/22 ; C12N15/63 ; C07K14/51
摘要:
The invention relates to polypeptide fragments of sclerostin and antibodies that bind to the fragments. The antibodies are useful in treating diseases of low bone density, such as osteoporosis, and in accelerating the healing of bone fractures.
公开/授权文献
- EP2301961B9 SCLEROSTIN EPITOPES 公开/授权日:2023-12-13
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