发明授权
EP2305194B1 A buprenorphine transdermal patch for use in the treatment of pain for a dosing interval of at least 7 days 无效
透皮贴剂具有为丁丙诺啡在治疗疼痛的用途为7天的给药间隔

A buprenorphine transdermal patch for use in the treatment of pain for a dosing interval of at least 7 days
摘要:
A sustained release formulation of buprenorphine is new. The composition comprises a transdermal delivery device which provides a first order release of buprenorphine over a 3-day dosing interval so that a maximum plasma concentration of 20 10 1052 pg/ml is obtained. the device then provides zero order kinetics over at least 2 more days.
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