发明公开
EP2310495A4 COMPOSITIONS AND METHODS FOR THE PRODUCTION OF ALPHA-HERPESVIRUSES
有权
ZUSAMMENSETZUNGEN UND VERFAHREN ZUR HERSTELLUNG DES ALPHA-HERPESVIRUS
- 专利标题： COMPOSITIONS AND METHODS FOR THE PRODUCTION OF ALPHA-HERPESVIRUSES
- 专利标题（中）： ZUSAMMENSETZUNGEN UND VERFAHREN ZUR HERSTELLUNG DES ALPHA-HERPESVIRUS
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申请号： EP09807164申请日： 2009-08-11
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公开(公告)号： EP2310495A4公开(公告)日： 2012-01-25
- 发明人: DELAGRAVE SIMON , OUBELAID RACHID , HAMBERGER JOHN
- 申请人： SANOFI PASTEUR BIOLOGICS CO
- 专利权人： SANOFI PASTEUR BIOLOGICS CO
- 当前专利权人： SANOFI PASTEUR BIOLOGICS CO
- 优先权： US18855208 2008-08-11
- 主分类号： C12N7/00
- IPC分类号： C12N7/00 ; C12N5/00 ; C12N7/01 ; C12N7/02
摘要：
The present invention relates to virus growth media that improve the yield of alpha-herpesviruses (e.g., HSV-2) grown in cell cultures. The growth media of the invention include two additives, a disaccharide and a lipid mixture, that can be added to serum-free or serum-enriched growth media to improve the efficiency of virus production. The invention further provides methods of producing alpha-herpesviruses (e.g., HSV-2) in such growth media.
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