This invention comprises shoes having pharmacotherapy functions, the insoles placed in said shoes are configured with troughs in which arbitrary numbers of containers of arbitrary geometry, at the bottoms of the containers bottom brackets are equipped, in which powdered preparations, liquid preparations and essential oil compositions are loaded, the medicinal function is percutaneously absorbed from the feet to promote unobstructed circulation and microcirculation and to activate cells, and finally, to contribute to the pharmacotherapy and healthcare of the human body.