发明公开
EP2319843A1 Substituted pyrrole derivatives and their use as HMG-CO inhibitors
有权
替代物Pyrrolderivate和Ihre Verwendung als HMG-CO-Hemmer
- 专利标题： Substituted pyrrole derivatives and their use as HMG-CO inhibitors
- 专利标题（中）： 替代物Pyrrolderivate和Ihre Verwendung als HMG-CO-Hemmer
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申请号： EP10179877.5申请日： 2004-05-28
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公开(公告)号： EP2319843A1公开(公告)日： 2011-05-11
- 发明人: Salman, Mohammad , Sattiegeri, Jitendra , Kumar, Yatendra , Aryan, Ram, Chander , Ramanthan, Vikram, Krishna , Chugh, Anita
- 申请人： Ranbaxy Laboratories Limited
- 申请人地址： Plot No. 90, Sector-32 Gurgaon - 122001, Haryana IN
- 专利权人： Ranbaxy Laboratories Limited
- 当前专利权人： Ranbaxy Laboratories Limited
- 当前专利权人地址： Plot No. 90, Sector-32 Gurgaon - 122001, Haryana IN
- 代理机构： Cronin, Brian Harold John
- 优先权： US449418 20030530
- 主分类号： C07D405/06
- IPC分类号： C07D405/06 ; C07D207/34 ; C07D401/12 ; C07D405/14 ; A61K31/40 ; A61K31/366
摘要：
The present invention relates to substituted pyrrole derivatives, which can be used as 2-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors. Compounds disclosed herein can function as cholesterol lowering agents and can be used for the treatment of cholesterol-related diseases and related symptoms. Processes for the preparation of disclosed compounds are provided, as well as pharmaceutical compositions containing the disclosed compounds, and methods of treating cholesterol-related diseases and related symptoms.
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