发明公开
EP2322526A1 Crystalline form of pemetrexed diacid and process for the preparation thereof 审中-公开
Kristalline Form von Pemetrexed-Disäureund Verfahren zu deren Herstellung

  • 专利标题: Crystalline form of pemetrexed diacid and process for the preparation thereof
  • 专利标题(中): Kristalline Form von Pemetrexed-Disäureund Verfahren zu deren Herstellung
  • 申请号: EP10179122.6
    申请日: 2007-08-14
  • 公开(公告)号: EP2322526A1
    公开(公告)日: 2011-05-18
  • 发明人: Busolli, JonathanDiulgheroff, NicolaNemethne, Racz, CsillaPirkes, MoranPontiroli, AlessandroVilla, MacroAronhime, Judith
  • 申请人: Sicor, Inc.
  • 申请人地址: 19 Hughes Irvine, CA 92618 US
  • 专利权人: Sicor, Inc.
  • 当前专利权人: Sicor, Inc.
  • 当前专利权人地址: 19 Hughes Irvine, CA 92618 US
  • 代理机构: King, Lawrence
  • 优先权: US837303P 20060814; US837637P 20060815; US839551P 20060822; US845031P 20060914; US847291P 20060925; US855139P 20061030; US860557P 20061121; US860554P 20061121; US880179P 20070111; US880178P 20070111; US899928P 20070206; US936553P 20070620; US958326P 20070702; US958213P 20070703; US958413P 20070705
  • 主分类号: C07D487/04
  • IPC分类号: C07D487/04
Crystalline form of pemetrexed diacid and process for the preparation thereof
摘要:
This invention relates a crystalline form of N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid, pemetrexed diacid, and to a process for the preparation thereof.
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