发明公开
- 专利标题： MICRONEEDLE DEVICE, AND METHOD FOR ENHANCING THE EFFICACY OF INFLUENZA VACCINE BY USING MICRONEEDLE DEVIVE
- 专利标题（中）： 微针装置和方法改进流感疫苗的效率利用微针装置
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申请号： EP09773249.9申请日： 2009-05-22
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公开(公告)号： EP2327419A1公开(公告)日： 2011-06-01
- 发明人: NOZAKI Chikateru , KAMINAKA Kazuyoshi , MATSUDA Junichi , TERAHARA Takaaki , KUWAHARA Tetsuji , TOKUMOTO Seiji
- 申请人： Hisamitsu Pharmaceutical Co., Inc. , Juridical Foundation The Chemo-Sero-Therapeutic Research Institute
- 申请人地址： 408, Tashirodaikanmachi Tosu-shi Saga 841-0017 JP
- 专利权人： Hisamitsu Pharmaceutical Co., Inc.,Juridical Foundation The Chemo-Sero-Therapeutic Research Institute
- 当前专利权人： Hisamitsu Pharmaceutical Co., Inc.,Juridical Foundation The Chemo-Sero-Therapeutic Research Institute
- 当前专利权人地址： 408, Tashirodaikanmachi Tosu-shi Saga 841-0017 JP
- 代理机构： Westendorp | Sommer
- 优先权： JP2008170220 20080630; JP2008267322 20081016
- 国际公布： WO2010001671 20100107
- 主分类号： A61K39/145
- IPC分类号： A61K39/145 ; A61K9/00 ; A61K9/70 ; A61K39/00 ; A61K39/39 ; A61K47/10 ; A61K47/34 ; A61K47/36 ; A61L31/00 ; A61M37/00 ; A61P31/16
摘要：
The present invention provides a method for enhancing the immunogenicity using a microneedle device capable of enhancing the immunogenicity of an influenza vaccine. According to the method for enhancing the immunogenicity using the present microneedle device, a microneedle device having microneedles made of polylactic acid, coated with an influenza vaccine composed of an antigen having type A strain (H1N1), type A strain (H3N2), and type B strain as active ingredients is brought into direct contact with the skin so as to transcutaneously administer the aforementioned influenza vaccine. After the transcutaneous administration, lauryl alcohol is applied to the site of the skin where the microneedle device has been brought into direct contact.
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