发明公开
- 专利标题： PROTECTED MONOMERS AND METHODS OF DEPROTECTION FOR RNA SYNTHESIS
- 专利标题（中）： RNA合成保护的单体和脱保护
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申请号： EP09815409.9申请日： 2009-09-22
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公开(公告)号： EP2331558A2公开(公告)日： 2011-06-15
- 发明人: DELLINGER, Douglas, J. , MYERSON, Joel , SIERZCHALA, Agnieszka , DELLINGEN, Geraldine, F. , TIMAR, Zoltan
- 申请人： Agilent Technologies, Inc.
- 申请人地址： 5301 Stevens Creek Boulevard Santa Clara, CA 95051 US
- 专利权人： Agilent Technologies, Inc.
- 当前专利权人： Agilent Technologies, Inc.
- 当前专利权人地址： 5301 Stevens Creek Boulevard Santa Clara, CA 95051 US
- 代理机构： Barth, Daniel Mathias
- 优先权： US466326 20090514; US99131P 20080922
- 国际公布： WO2010034024 20100325
- 主分类号： C07H21/02
- IPC分类号： C07H21/02 ; C07H21/00
摘要：
A nucleoside monomer that is protected by a thionocarbamate protecting group is provided, as well as a method for making a polynucleotide that uses the same. Also provided is a polynucleotide synthesis method that employs a diamine to deprotect a protected polynucleotide.
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