The present invention relates to a composition of extracts from plants which can be used for prophylaxis or treatment of metabolism disorder of blood lipid, which belongs to the pharmaceutical technology. The plant extract composition provided by the present invention includes the following ingredients in weight: 3-10 portions of oleanolic acid, 1-5 portions of salvianolic acid, 1-5 portions of danshensu, 1-3 portions of berberine, 1-5 portions of panax notoginseng saponins, 1-5 portions of polysaccharides of atracty-lodes macrocephala koidz, 1-3 portions of aucubin, 1-5 portions of total flavone in cirsium japonicum, 1-5 portions of fmger citron polysaccharide, 1-5 portions of panax notoginseng polysaccharides and 1-5 portions of flavones. The present invention also provides the use of such composition in manufacturing medicaments used for prophylaxis or treatment of diseases related to metabolism disorder of blood lipid, and the use of such composition in manufacturing health food used for adjuvant prophylaxis or treatment of diseases related to metabolism disorder of blood lipid. The plant extract composition provided by the present invention has broadened the application of the existing technology in the field of pharmaceutical preparations, which significantly improves the bioavailability, increase the effectiveness, stability, controllability, convenience and safety of medication.