发明公开
EP2343279A4 FUSED-RING DERIVATIVE AND MEDICAL APPLICATION OF SAME
有权
RINGKONDENSIERTES DERIVAT UND MEDISINISCHE ANWENDUNG DAVON
- 专利标题: FUSED-RING DERIVATIVE AND MEDICAL APPLICATION OF SAME
- 专利标题(中): RINGKONDENSIERTES DERIVAT UND MEDISINISCHE ANWENDUNG DAVON
-
申请号: EP09820583申请日: 2009-10-14
-
公开(公告)号: EP2343279A4公开(公告)日: 2014-08-06
- 发明人: SHIMIZU KAZUO , IIZUKA MASATO , FUJIKURA HIDEKI , TAKIGAWA YASUSHI , HIRATOCHI MASAHIRO
- 申请人: KISSEI PHARMACEUTICAL
- 专利权人: KISSEI PHARMACEUTICAL
- 当前专利权人: KISSEI PHARMACEUTICAL
- 优先权: JP2008266088 2008-10-15
- 主分类号: C07D213/79
- IPC分类号: C07D213/79 ; A61K31/192 ; A61K31/415 ; A61K31/426 ; A61K31/44 ; A61K31/47 ; A61P3/00 ; A61P13/04 ; A61P13/12 ; A61P19/00 ; A61P19/06 ; C07C255/57 ; C07D215/50 ; C07D231/14 ; C07D277/20 ; C07D277/56
摘要:
The present invention provides compounds useful as agents for the prevention or treatment of a disease associated with abnormal plasma uric acid level and the like. The present invention relates to fused ring derivatives represented by the following formula (I) having xanthine oxidase inhibitory activities and useful as agents for the prevention or treatment of a disease associated with abnormality of plasma uric acid level, prodrugs thereof, salts thereof or the like. In the formula (I), X 1 and X 2 represent CH or N; ring U represents aryl or heteroaryl; m represents integral number from 0 to 2; n represents integral number from 0 to 3; R 1 represents a hydroxy group, amino or C 1-6 alkyl; R 2 represents C 1-6 alkyl, C 1-6 alkoxy C 1-6 alkyl or the like.
信息查询
IPC分类: