发明公开
- 专利标题： FOLATE RECEPTOR BINDING CONJUGATES OF ANTIFOLATES
- 专利标题（中）： 叶酸受体BINDUNGSKONJUGATE抗叶酸剂
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申请号： EP09815218申请日： 2009-09-17
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公开(公告)号： EP2349274A4公开(公告)日： 2014-12-17
- 发明人: LEAMON CHRISTOPHER PAUL , VLAHOV IONTCHO RADOSLAVOV , LOW PHILIP STEWART
- 申请人： ENDOCYTE INC , PURDUE RESEARCH FOUNDATION
- 专利权人： ENDOCYTE INC,PURDUE RESEARCH FOUNDATION
- 当前专利权人： ENDOCYTE INC,PURDUE RESEARCH FOUNDATION
- 优先权： US9765508 2008-09-17
- 主分类号： A61K31/517
- IPC分类号： A61K31/517 ; A61K47/48 ; A61P11/06
摘要：
Conjugates of antifolates, releasable linkers, and drugs, and pharmaceutical compositions containing them are described. The conjugates are useful for treating diseases arising from pathogenic cell populations. Methods for treating such diseases are also described.
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