发明公开
- 专利标题： ISONICOTINAMIDE OREXIN RECEPTOR ANTAGONISTS
- 专利标题（中）： ISONIKOTINAMIDE ALS食欲素受体拮抗剂
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申请号： EP09741173.0申请日： 2009-10-26
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公开(公告)号： EP2350010A1公开(公告)日： 2011-08-03
- 发明人: BERGMAN, Jeffrey, M. , COLEMAN, Paul, J. , MATTERN, Mamio Christa , MERCER, Swati, P. , REGER, Thomas, S. , ROECKER, Anthony, J.
- 申请人： Merck Sharp & Dohme Corp.
- 申请人地址： 126 East Lincoln Avenue Rahway, NJ 07065-0907 US
- 专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人地址： 126 East Lincoln Avenue Rahway, NJ 07065-0907 US
- 代理机构： Buchan, Gavin MacNicol
- 优先权： US197789P 20081030; US180574P 20090522
- 国际公布： WO2010051236 20100506
- 主分类号： C07D213/81
- IPC分类号： C07D213/81 ; C07D401/04 ; C07D401/12 ; C07D401/14 ; C07D417/14
摘要：
The present invention is directed to isonicotinamide compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved.
公开/授权文献
- EP2350010B1 ISONICOTINAMIDE OREXIN RECEPTOR ANTAGONISTS 公开/授权日：2014-03-26
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