发明公开
EP2352022A1 IONIZATION METHOD AND APPARATUS WITH PROBE, AND ANALYTICAL METHOD AND APPARATUS
有权
VONRICHTUNG VONRICHTUNG MIT SONDE SOWIE ANALYSEVERFAHREN发行VORRICHTUNG
- 专利标题: IONIZATION METHOD AND APPARATUS WITH PROBE, AND ANALYTICAL METHOD AND APPARATUS
- 专利标题(中): VONRICHTUNG VONRICHTUNG MIT SONDE SOWIE ANALYSEVERFAHREN发行VORRICHTUNG
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申请号: EP09822096.5申请日: 2009-10-19
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公开(公告)号: EP2352022A1公开(公告)日: 2011-08-03
- 发明人: HIRAOKA, Kenzo
- 申请人: University of Yamanashi
- 申请人地址: 4 - 37, Takeda 4-chome Kofu-shi Yamanashi 400-8510 JP
- 专利权人: University of Yamanashi
- 当前专利权人: University of Yamanashi
- 当前专利权人地址: 4 - 37, Takeda 4-chome Kofu-shi Yamanashi 400-8510 JP
- 代理机构: Käck, Jürgen
- 优先权: JP2008271954 20081022
- 国际公布: WO2010047399 20100429
- 主分类号: G01N27/62
- IPC分类号: G01N27/62 ; G01N27/64 ; H01J49/10
摘要:
The tip of an electrically conductive probe 11 is brought into contact with a sample and captures the sample S under atmospheric pressure, a high voltage for electrospray is applied to the probe 11 while a solvent is supplied to the tip of the probe 11 that has captured the sample, and molecules of the sample S at the probe tip are ionized. A miniscule amount of a fine solvent droplet is supplied to the probe tip and slow electrospray is implemented. As a result, the size of the electrically charged droplet can be made extremely small and components within the sample can be analyzed extensively without selectivity. Further, in imaging over an extended period of time, electrospray is possible even in the event that the sample dries.
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