发明公开
EP2354159A1 CCL17 inhibitors for use in T helper cell-driven diseases
审中-公开
CCL17-Inhibitoren zur Verwendung bei von T-Helferzellen gesteuerten Erkrankungen
- 专利标题: CCL17 inhibitors for use in T helper cell-driven diseases
- 专利标题(中): CCL17-Inhibitoren zur Verwendung bei von T-Helferzellen gesteuerten Erkrankungen
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申请号: EP10001208.7申请日: 2010-02-05
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公开(公告)号: EP2354159A1公开(公告)日: 2011-08-10
- 发明人: Zernecke, Alma, Dr. , Weber, Christian, Dr.
- 申请人: RWTH Aachen
- 申请人地址: Templergraben 55 52062 Aachen DE
- 专利权人: RWTH Aachen
- 当前专利权人: RWTH Aachen
- 当前专利权人地址: Templergraben 55 52062 Aachen DE
- 代理机构: Michalski Hüttermann & Partner Patentanwälte
- 主分类号: C07K16/24
- IPC分类号: C07K16/24 ; C07K14/52 ; C07K14/775
摘要:
The present invention is based on the studies of the pathogenic role of CCL17-expressing DCs and their effector function in inflammatory diseases, particularly in atherosclerotic diseases. It relates to agents inhibiting the binding reaction between a CCL17 cytokine and a CCL17 receptor for use as a medicament ( Fig. 5a ).
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