发明公开
EP2358662A1 PROCEDE D'AMMONOLYSE DE L'ACIDE 11-BROMOUNDECANOÏQUE 有权
11溴代十一烷的方法氨解

  • 专利标题: PROCEDE D'AMMONOLYSE DE L'ACIDE 11-BROMOUNDECANOÏQUE
  • 专利标题(英): Process for the ammonolysis of 11-bromoundecanoic acid
  • 专利标题(中): 11溴代十一烷的方法氨解
  • 申请号: EP09802175.1
    申请日: 2009-12-15
  • 公开(公告)号: EP2358662A1
    公开(公告)日: 2011-08-24
  • 发明人: PEES, BernardLEBRUN, Stephanie
  • 申请人: Arkema France
  • 申请人地址: 420, rue d'Estienne d'Orves 92700 Colombes FR
  • 专利权人: Arkema France
  • 当前专利权人: Arkema France
  • 当前专利权人地址: 420, rue d'Estienne d'Orves 92700 Colombes FR
  • 代理机构: Lhoste, Catherine
  • 优先权: FR0807259 20081219
  • 国际公布: WO2010070228 20100624
  • 主分类号: C07C227/08
  • IPC分类号: C07C227/08 C07C229/08
PROCEDE D'AMMONOLYSE DE L'ACIDE 11-BROMOUNDECANOÏQUE
摘要:
The invention relates to a process for the ammonolysis of 11‑bromoundecanoic acid, carried out under conditions that make it possible to limit secondary reactions that produce impurities, especially secondary amine type reactions, while considerably reducing the reaction time. According to the invention, the process comprises the following steps: i) a step of dispersing 11‑bromoundecanoic acid, molten or non-molten, in an aqueous solution of ammonia, and ii) an ammonolysis step comprising the reaction of 11-bromoundecanoic acid with excess ammonia water, under conditions whereby the reaction medium is stirred and heated gradually so as to obtain 11-aminoundecanoic acid with total consumption of the 11-bromoundecanoic acid.
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