发明公开
EP2360258A3 Aprotinin polypeptides for transporting a compound across the blood-brain barrier
有权
Aprotininpolypeptide用于跨血脑屏障输送化合物
- 专利标题: Aprotinin polypeptides for transporting a compound across the blood-brain barrier
- 专利标题(中): Aprotininpolypeptide用于跨血脑屏障输送化合物
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申请号: EP11000946.1申请日: 2005-07-21
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公开(公告)号: EP2360258A3公开(公告)日: 2011-12-14
- 发明人: Beliveau, Richard , Demeule, Michel , Che, Christian , Regina, Anthony
- 申请人: Angiochem Inc.
- 申请人地址: 201 President Kennedy Avenue Suite PK-R220 Montréal, QC H2X 3Y7 CA
- 专利权人: Angiochem Inc.
- 当前专利权人: Angiochem Inc.
- 当前专利权人地址: 201 President Kennedy Avenue Suite PK-R220 Montréal, QC H2X 3Y7 CA
- 代理机构: Lahrtz, Fritz
- 优先权: US653928P 20050218
- 主分类号: C12N15/15
- IPC分类号: C12N15/15 ; C07K14/81 ; A61K47/48 ; A61K47/42 ; A61K51/08 ; A61K49/14 ; A61P25/00
摘要:
The invention relates to improvements in the field of drug delivery. More particularly, the invention relates to polypeptides derived from aprotinin and from aprotinin analogs as well as conjugates and pharmaceutical compositions comprising these polypeptides or conjugates. The present invention also relates to the use of these polypeptide for transporting a compound or drug across the blood-brain barrier of a mammal and in the treatment and diagnosis of neurological diseases.
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