发明公开
- 专利标题： Styrylpyridine derivatives and their use for binding and imaging amyloid plaques
- 专利标题（中）： 亚利桑那州立大学维多利亚州立大学
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申请号： EP11152124.1申请日： 2007-03-26
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公开(公告)号： EP2363392A1公开(公告)日： 2011-09-07
- 发明人: Kung, Hank F. , Kung, Mei-Ping
- 申请人： The Trustees of The University of Pennsylvania
- 申请人地址： Center for Technology Transfer, 3160 Chestnut Street, Suite 200 Philadelphia, Pennsylvania 19104 US
- 专利权人： The Trustees of The University of Pennsylvania
- 当前专利权人： The Trustees of The University of Pennsylvania
- 当前专利权人地址： Center for Technology Transfer, 3160 Chestnut Street, Suite 200 Philadelphia, Pennsylvania 19104 US
- 代理机构： Dörries, Hans Ulrich
- 优先权： US787156P 20060330
- 主分类号： C07D213/16
- IPC分类号： C07D213/16 ; A61K51/04
摘要：
This invention relates to a method of imaging amyloid deposits and to styrylpyridine compounds, and methods of making radiolabeled styrylpyridine compounds useful in imaging amyloid deposits. This invention also relates to compounds, and methods of making compounds for inhibiting the aggregation of amyloid proteins to form amyloid deposits, and a method of delivering a therapeutic agent to amyloid deposits.
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