发明公开
- 专利标题: TNIK INHIBITOR AND THE USE
- 专利标题(中): TNIK抑制剂及其用途
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申请号: EP09796056.1申请日: 2009-11-30
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公开(公告)号: EP2364149A1公开(公告)日: 2011-09-14
- 发明人: YAMADA, Tesshi , SHITASHIGE, Miki , YOKOTA, Koichi , SAWA, Masaaki , MORIYAMA, Hideki
- 申请人: National Cancer Center , Carna Biosciences Inc.
- 申请人地址: 5-1-1, Tsukiji, Chuo-ku Tokyo 104-0045 JP
- 专利权人: National Cancer Center,Carna Biosciences Inc.
- 当前专利权人: National Cancer Center,Carna Biosciences Inc.
- 当前专利权人地址: 5-1-1, Tsukiji, Chuo-ku Tokyo 104-0045 JP
- 代理机构: TBK
- 优先权: US118809P 20081201; US503374 20090715
- 国际公布: WO2010064111 20100610
- 主分类号: A61K31/426
- IPC分类号: A61K31/426 ; C07D277/56 ; A61P35/00
摘要:
The present invention relates to Traf2- and Nck-interacting kinase (TNIK) inhibitors, pharmaceutical compositions, and methods for the treatment of cancer patients with TNIK inhibitors. And the present invention relates to a novel aminothiazole derivatives. The TNIK inhibitors are showed by a next formula (I). (I) Wherein R1, R2, R3, R4, R5 and R6 represent independently a hydrogen atom or a substituent group.
公开/授权文献
- EP2364149B1 TNIK INHIBITOR AND THE USE 公开/授权日:2014-05-07
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