发明公开
EP2370396A4 METHOD FOR SELECTIVELY CRYSTALLIZING A Z ISOMER OF IOPROMIDE
审中-公开
VERFAHREN ZUR SELEKTIVEN KRISTALLISIERUNG EINES Z-ISOMERS VON IOPROMID
- 专利标题： METHOD FOR SELECTIVELY CRYSTALLIZING A Z ISOMER OF IOPROMIDE
- 专利标题（中）： VERFAHREN ZUR SELEKTIVEN KRISTALLISIERUNG EINES Z-ISOMERS VON IOPROMID
-
申请号： EP09830523申请日： 2009-10-12
-
公开(公告)号： EP2370396A4公开(公告)日： 2012-04-25
- 发明人: CHOI SOO-JIN , LEE BYUNG-GOO , LEE HAN-KUK , LIM YOUNG-MOOK , KIM WOL-YOUNG , LEE JOON-HWAN
- 申请人： DAE WOONG PHARMA
- 专利权人： DAE WOONG PHARMA
- 当前专利权人： DAE WOONG PHARMA
- 优先权： KR20080123138 2008-12-05
- 主分类号： C07C231/20
- IPC分类号： C07C231/20 ; A61K31/167 ; C07C233/69 ; C07C237/46
摘要：
The present invention relates to a method for selectively crystallizing Z isomer of iopromide of formula (I) comprising a) dissolving a crude iopromide comprising a mixture of E and Z isomers or a concentrate thereof in an alcohol, and b) heating the resulting alcohol solution to obtain crystalline of Z isomer of iopromide; and a method for preparing a composition comprising the crystalline Z isomer of iopromide.
信息查询
