发明公开
EP2370580A2 TREATMENT OF SIRTUIN 1 (SIRT1) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO SIRTUIN 1
审中-公开
抗衰老酶1处理(SIRT1)-BEDINGTEN病从天然反义转录针对抗衰老酶抑制1
- 专利标题: TREATMENT OF SIRTUIN 1 (SIRT1) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO SIRTUIN 1
- 专利标题(中): 抗衰老酶1处理(SIRT1)-BEDINGTEN病从天然反义转录针对抗衰老酶抑制1
-
申请号: EP09831068.3申请日: 2009-12-02
-
公开(公告)号: EP2370580A2公开(公告)日: 2011-10-05
- 发明人: COLLARD, Joseph , KHORKOVA SHERMAN, Olga , COITO, Carlos , DE LEON, Belinda
- 申请人: Opko Curna, LLC
- 申请人地址: 4400 Biscayne Boulevard Miami, FL 33137 US
- 专利权人: Opko Curna, LLC
- 当前专利权人: Opko Curna, LLC
- 当前专利权人地址: 4400 Biscayne Boulevard Miami, FL 33137 US
- 代理机构: Evenson, Jane Harriet
- 优先权: US157255P 20090304; US119965P 20081204; US259072P 20091106
- 国际公布: WO2010065662 20100610
- 主分类号: C12N15/63
- IPC分类号: C12N15/63 ; C12N15/11 ; C07H19/00 ; A61K31/712 ; C12Q1/68
摘要:
Oligonucleotide compounds modulate expression and/or function of Sirtuin 1 (SIRT1) polynucleotides and encoded products thereof. Methods for treating diseases associated with Sirtuin 1 (SIRT1) comprise administering one or more Oligonucleotide compounds designed to inhibit the SIRT1 natural antisense transcript to patients.
公开/授权文献
信息查询
IPC分类: