发明公开
- 专利标题： NOVEL POLYMORPHS OF SUNITINIB MALATE
- 专利标题（中）： 新的多晶型舒尼替尼OFF MALAT
-
申请号： EP09836178.5申请日： 2009-01-02
-
公开(公告)号： EP2373643A2公开(公告)日： 2011-10-12
- 发明人: PARTHASARADHI REDDY, Bandi , RATHNAKAR REDDY, Kura , RAJI REDDY, Rapolu , MURALIDHARA REDDY, Dasari , SRINIVASA RAO, Thungathurthy
- 申请人： Hetero Research Foundation
- 申请人地址： Plot No. B-80&81 A.P.I.E., Balanagar Hyderabad Andhrapradesh Hyderabad 500 018 IN
- 专利权人： Hetero Research Foundation
- 当前专利权人： Hetero Research Foundation
- 当前专利权人地址： Plot No. B-80&81 A.P.I.E., Balanagar Hyderabad Andhrapradesh Hyderabad 500 018 IN
- 代理机构： Green, Mark Charles
- 国际公布： WO2010076805 20100708
- 主分类号： C07D403/06
- IPC分类号： C07D403/06
摘要：
The present invention provides a novel crystalline form of sunitinib malate, process for its preparation and to pharmaceutical composition containing it. The present invention also provides a process for preparation of sunitinib malate crystal form I. Thus, for example, sunitinib malate was added to water, the mixture was heated to 80 deg C to obtain a clear solution and stirred for 30 minutes at 80 deg C, slowly cooled to room temperature and the solution was subjected to freez drying at about -90 deg C for 8 hours to give sunitinib malate crystalline form III.
信息查询
