发明公开
EP2377547A1 Use of IL-21 as an antimicrobial agent
审中-公开
Verwendung von IL-21 als antimikrobielles Mittel
- 专利标题: Use of IL-21 as an antimicrobial agent
- 专利标题(中): Verwendung von IL-21 als antimikrobielles Mittel
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申请号: EP11169010.3申请日: 2003-06-06
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公开(公告)号: EP2377547A1公开(公告)日: 2011-10-19
- 发明人: Nelson, Andrew J. , Hughes, Steven D. , Holly, Richard D. , Kindsvogel, Wayne, R.
- 申请人: ZymoGenetics, Inc.
- 申请人地址: 1201 Eastlake Avenue East Seattle, Washington 98102 US
- 专利权人: ZymoGenetics, Inc.
- 当前专利权人: ZymoGenetics, Inc.
- 当前专利权人地址: 1201 Eastlake Avenue East Seattle, Washington 98102 US
- 代理机构: Griffin, Philippa Jane
- 优先权: US387127P 20020607
- 主分类号: A61K38/20
- IPC分类号: A61K38/20 ; A61K39/00 ; A61P31/04 ; A61P31/10 ; A61P33/02 ; C07K14/54
摘要:
There is provided a polypeptide having a functional activity of IL-21 wherein the polypeptide has at least 80% identity to an IL-21 polypeptide comprising residues 41 (Gln) to 148 (Ile) of SEQ ID NO:2 or residues 32 (Gln) to 162 (Ser) of SEQ ID NO:2, for use in treating a microbial infection in a mammal.
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